What if I Have Problems With Treatment?

  • DACOGEN may cause side effects
  • Please call 1-800-438-9927 to report any adverse event while taking DACOGEN
  • If you are having side effects, your healthcare provider may be able to offer tips on how you can help manage certain side effects
  • The tips provided here are for information and not to take the place of your healthcare provider's advice. Make sure you follow your healthcare provider's instructions
If your healthcare provider says you have a low white blood cell count, you may want to try the following tips:
  • Wash your hands with soap and water before cooking or eating and after using the bathroom
  • Stay away from people who are sick
  • Stay away from crowds
  • Take care of your teeth and skin
  • Disinfect cuts right away

If your healthcare provider says you have a low red blood cell count, you may want to try the following tips:

Balance rest
and activities

Eat a
balanced diet

Drink a lot
of water

If your healthcare provider says you have a low platelet count, you may want to try the following tips:

Brush your teeth with
a soft toothbrush

Be extra careful with
knives and scissors

Use an
electric razor

INDICATION:

DACOGEN is a prescription medicine indicated for treatment of patients with myelodysplastic syndromes (MDS), including:

Previously treated and untreated MDS
De novo (cause unknown) and secondary (treatment-related) MDS:
  • All French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia)
  • Intermediate-1, intermediate-2, and high-risk International Prognostic Scoring System (IPSS) groups

IMPORTANT SAFETY INFORMATION:

Treatment with DACOGEN is associated with serious, sometimes fatal, blood disorders including:
  • fewer white blood cells (neutropenia and leukopenia), platelets (thrombocytopenia), and/or red blood cells (anemia)
  • fever associated with low white blood cell counts (febrile neutropenia)
  • bone marrow suppression
  • infections
Your doctor will test and monitor your blood cells before and during treatment with DACOGEN. Your doctor may prescribe medicine to help manage your blood cell counts and/or medicines to prevent or treat infections. Your doctor may need to delay your treatment and/or reduce your dose if you experience certain side effects. Patients should monitor and report any symptoms or fever to their doctor as soon as possible
Harm to a fetus when administered to a pregnant woman: Women of childbearing potential and men with female partners of childbearing potential should use effective contraception and avoid pregnancy while taking DACOGEN
Other common side effects including:
  • feeling tired (fatigue)
  • fever (pyrexia)
  • nausea
  • cough
  • reddish or purplish spots (petechiae)
  • constipation
  • diarrhea
  • high blood sugar (hyperglycemia)
DACOGEN should be used with caution if you have kidney or liver problems

You are encouraged to report side effects of DACOGEN® (decitabine), please contact Otsuka America Pharmaceutical, Inc. at 1-800-438-9927 or FDA at 1-800-FDA1088 (www.fda.gov/medwatch).

Please see FULL PRESCRIBING INFORMATION