Dacogen

TYPES OF MDS TREATMENT

Only your doctor can determine which treatment is right for you. There are several treatments, but not every one is right for every person. Ask your doctor which treatment is right for you.

Supportive care:

Patients receive red blood cell and/or platelet transfusions, antibiotics, and other medications such as blood cell growth factors which stimulate blood cell production. These treatments are intended to control symptoms and to prevent infections. The main goal of supportive care therapy is to relieve symptoms of the disease and prevent problems from low blood counts.

Hypomethylating Agents:

DACOGEN is a hypomethylating agent that is designed to fight the underlying disease rather than just relieving the symptoms. Treatment with DACOGEN may lead to normal production of red blood cells, white blood cells and platelets. As a result, a patient’s symptoms may improve and the need for blood transfusions and growth factors may be reduced or eliminated.

Chemotherapy:

Chemotherapy drugs kill cells in the blood and marrow. Chemotherapy often involves the use of a combination of drugs to stop the growth of rapidly dividing cells.

Stem Cell Transplant:

Stem cell transplant is the only potential cure for MDS, but it is not for every patient.10 It is generally reserved for patients who are younger and have the physical ability to withstand the effects of the chemotherapy required prior to the transplant. During the procedure, the patient’s bone marrow is destroyed using chemotherapy and radiation. The bone marrow is then replaced with new, disease-free, blood-forming stem cells, oftentimes from a donor.

References

DACOGEN is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo, and secondary MDS of all FAB subtypes (RA, RARS, RAEB, RAEB-t, CMML) and Intermediate-1, Intermediate-2, and High-Risk IPSS groups.

DACOGEN may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant while using DACOGEN. Men should be advised not to father a child while receiving treatment with DACOGEN, and for 2 months afterwards. The most commonly occurring adverse reactions include neutropenia, thrombocytopenia, anemia, fatigue, pyrexia, nausea, cough, petechiae, constipation, diarrhea, and hyperglycemia.

DACOGEN is available by prescription only. Please see the important product information for DACOGEN for more information. This site does not contain everything that is known about DACOGEN. If you would like to know more, talk to your healthcare professional.