Dacogen

MANAGING MDS SYMPTOMS

The most common symptoms of myelodysplastic syndromes (MDS) are anemia (low red blood cell count), neutropenia (low white blood cell count) and thrombocytopenia (low platelet count).5

Anemia

Anemia is a blood disorder that is a common side effect of those with MDS. Anemia may cause extreme fatigue and loss of energy.

Tips on how to manage anemia:

  • Limit your activities to conserve energy
  • Get up slowly from lying or sitting positions to reduce dizziness
  • Ask your doctor about treatments that may help increase your red blood cell count
  • Plan your day to include short naps and rest breaks
  • Participate in light exercise, take short walks
  • Eat small meals frequently during the day
  • Drink plenty of fluids

Neutropenia

Neutropenia is a blood disorder that affects the white blood cells and prevents your body from fighting infections.

Precautions to take:

  • Frequently wash your hands
  • Bathe daily
  • Use a soft toothbrush for frequent, gentle mouth care
  • Avoid uncooked food or foods that cannot be washed
  • Regularly check your body temperature
  • Utilize an electric shaver rather than a razor
  • Take care to avoid bodily injury when using sharp objects
  • Use antiseptic to clean cuts

Thrombocytopenia

Thrombocytopenia is a type of blood disorder that causes low platelet counts. Low platelet counts may cause bruising or excessive bleeding.

Precautions to take:

  • Avoid taking any type of medication or drinking any alcoholic beverages unless your doctor approves
  • Use a soft tissue to gently blow your nose
  • Use a soft toothbrush
  • Take care not to burn or cut yourself
  • Use an electric shaver rather than a razor
  • Wear proper protective wear as necessary to minimize bodily injury

References

DACOGEN is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo, and secondary MDS of all FAB subtypes (RA, RARS, RAEB, RAEB-t, CMML) and Intermediate-1, Intermediate-2, and High-Risk IPSS groups.

DACOGEN may cause fetal harm when administered to a pregnant woman. Women of childbearing potential should be advised to avoid becoming pregnant while using DACOGEN. Men should be advised not to father a child while receiving treatment with DACOGEN, and for 2 months afterwards. The most commonly occurring adverse reactions include neutropenia, thrombocytopenia, anemia, fatigue, pyrexia, nausea, cough, petechiae, constipation, diarrhea, and hyperglycemia.

DACOGEN is available by prescription only. Please see the important product information for DACOGEN for more information. This site does not contain everything that is known about DACOGEN. If you would like to know more, talk to your healthcare professional.